Transformative high-tech solutions leverage ANR response

Demon rum: high-tech solutions to an age-old problem.

This article summarizes the proceedings of a symposium at the 2004 Research Society on Alcoholism Meeting in Vancouver, British Columbia, Canada, organized and chaired by Scott T. Walters. The purpose of the symposium was to describe several brief motivational interventions offered via the Internet, including the evidence for web-based interventions, applications and contexts in which such appr...

High Tech versus Low Tech Training

The United States Marine Corps has some of the most advanced weapons systems and training in the world, yet they make extensive use of “low tech” training tools. Sand table exercises and tactical decision games are used by Marines all over the world, at sea and on land. Although the U.S. Department of Defense has a nearly $18 billion annual training budget, the Marines choose to teach decision ...

High Tech Rankings, Specialization and Relationship to Growth: A Response

High-TECh thymus.

ased assessment of associations with disease phenotypes. This approach relieves the investigator of having to conjure up candidate genes, and will lead to unexpected and often inexplicable findings, as have been reported for diabetes, a prime example of a multigenic trait.3 To query such a large number of SNPs, patient samples must be substantial and the analytical approach must be rigorous. Ne...

High-tech hazards.

In silico screening methods based on the 3D structures of the ligands or of the proteins have become an essential tool to facilitate the drug discovery process. To achieve such process, the 3D structures of the small chemical compounds have to be generated. In addition, for ligand-based screening computations or hierarchical structurebased screening projects involving a rigid-body docking step,...